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Stephen S Hecht Selected Research

Acetylcysteine (Siran)

1/2023Association of Urinary Biomarkers of Smoking-Related Toxicants with Lung Cancer Incidence in Smokers: The Multiethnic Cohort Study.
4/2012Urinary levels of volatile organic carcinogen and toxicant biomarkers in relation to lung cancer development in smokers.
9/2005Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.
9/2002Inhibition of lung tumorigenesis in A/J mice by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-L-cysteine and myo-inositol, individually and in combination.

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Stephen S Hecht Research Topics

Disease

106Neoplasms (Cancer)
03/2024 - 01/2002
68Lung Neoplasms (Lung Cancer)
01/2023 - 04/2002
66Carcinogenesis
01/2023 - 09/2002
10Inflammation (Inflammations)
01/2023 - 01/2014
7Adenoma (Adenomas)
01/2021 - 09/2005
7Esophageal Neoplasms (Esophageal Cancer)
12/2016 - 02/2003
5Tobacco Use Disorder (Nicotine Dependence)
01/2022 - 09/2007
5Head and Neck Neoplasms (Head and Neck Cancer)
09/2017 - 03/2012
3Hepatocellular Carcinoma (Hepatoma)
01/2019 - 11/2005
3Squamous Cell Carcinoma of Head and Neck
09/2017 - 08/2013
3Leukemia
12/2015 - 04/2010
3Adenocarcinoma of Lung
02/2010 - 09/2005
3Adenocarcinoma
02/2010 - 09/2005
2Pancreatic Neoplasms (Pancreatic Cancer)
02/2024 - 01/2010
2Mouth Neoplasms (Oral Cancer)
10/2023 - 01/2014
2Substance Withdrawal Syndrome (Withdrawal Symptoms)
12/2019 - 01/2011
2Carcinoma (Carcinomatosis)
01/2018 - 03/2012
2Liver Neoplasms (Liver Cancer)
07/2014 - 12/2004

Drug/Important Bio-Agent (IBA)

90CarcinogensIBA
11/2023 - 01/2002
66Biomarkers (Surrogate Marker)IBA
02/2024 - 06/2002
48SmokeIBA
09/2023 - 01/2002
46DNA AdductsIBA
10/2023 - 08/2002
324- (N- methyl- N- nitrosamino)- 1- (3- pyridyl)- 1- butanoneIBA
03/2024 - 04/2002
26NitrosaminesIBA
03/2024 - 02/2003
26Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA
02/2024 - 12/2002
23DNA (Deoxyribonucleic Acid)IBA
03/2023 - 08/2002
19NicotineFDA Link
01/2023 - 10/2003
18N'-nitrosonornicotine (nitrosonornicotine)IBA
03/2024 - 05/2002
18CotinineIBA
01/2023 - 09/2007
144- (methylnitrosamino)- 1- (3- pyridyl)- 1- butan- 1- olIBA
12/2019 - 03/2008
14Benzo(a)pyreneIBA
01/2014 - 01/2002
11Acrolein (Aqualin)IBA
09/2023 - 04/2007
9phenanthreneIBA
01/2016 - 12/2004
8GlucuronidesIBA
08/2015 - 04/2005
7AcidsIBA
09/2023 - 07/2008
7phenethyl isothiocyanate (PEITC)IBA
01/2022 - 09/2002
7Benzene (Benzole)IBA
01/2022 - 01/2002
7nitrosamine 4- (methylnitrosamino)- 1- (3- pyridyl)- 1- butanoneIBA
01/2018 - 07/2008
7indole-3-carbinolIBA
01/2016 - 06/2004
6AcetaldehydeIBA
01/2021 - 02/2006
52-butenal (crotonaldehyde)IBA
09/2023 - 05/2010
5Proteins (Proteins, Gene)FDA Link
09/2023 - 09/2005
5Tobacco Smoke Pollution (Passive Smoking)IBA
01/2020 - 10/2006
5EnzymesIBA
01/2017 - 04/2005
5IsothiocyanatesIBA
07/2016 - 09/2002
5Epoxy Compounds (Epoxides)IBA
09/2014 - 03/2009
5Inositol (Myoinositol)IBA
09/2010 - 09/2002
4CreatinineIBA
01/2023 - 12/2003
4AldehydesIBA
01/2023 - 06/2011
4Acetylcysteine (Siran)FDA LinkGeneric
01/2023 - 09/2002
4O-(6)-methylguanineIBA
04/2022 - 01/2014
4Formaldehyde (Formol)FDA Link
01/2021 - 08/2007
47,8-dihydromethysticinIBA
01/2020 - 10/2014
4Phosphates (Orthophosphate)IBA
11/2019 - 11/2015
4Dinoprostone (PGE2)FDA Link
01/2019 - 07/2016
43,3'-diindolylmethane (diindolylmethane)IBA
01/2016 - 07/2007
4nitrosobenzylmethylamineIBA
01/2016 - 08/2006
4AflatoxinsIBA
01/2012 - 12/2004
4N- acetyl- S- (N- 2- phenethylthiocarbamoyl)- L- cysteineIBA
09/2010 - 09/2002
3r- 1,t- 2,3,c- 4- tetrahydroxy- 1,2,3,4- tetrahydrophenanthreneIBA
02/2024 - 01/2009
3phenanthrene tetraolIBA
01/2023 - 05/2014
3hydroxide ionIBA
01/2023 - 02/2014
3CytochromesIBA
04/2022 - 06/2009
3Environmental CarcinogensIBA
01/2022 - 08/2017
37- hydroxy- 5,11- dioxotetranorprostane- 1,16- dioic acidIBA
01/2019 - 01/2019
3Anthocyanins (Anthocyanin)IBA
01/2016 - 01/2009
3CytokinesIBA
01/2016 - 06/2014
31-hydroxypyreneIBA
08/2015 - 03/2008
3Glutathione (Reduced Glutathione)IBA
09/2010 - 03/2008
3Glutathione Transferase (Glutathione S-Transferase)IBA
09/2010 - 05/2008
3TransferasesIBA
03/2009 - 09/2005
3Proliferating Cell Nuclear Antigen (PCNA)IBA
12/2008 - 09/2005
3benzyl isothiocyanateIBA
03/2003 - 09/2002
2hydroxycotinineIBA
01/2023 - 01/2017
2Environmental Pollutants (Pollutants, Environmental)IBA
01/2020 - 01/2012
2F2-Isoprostanes (F2 Isoprostanes)IBA
01/2019 - 03/2008
2EicosanoidsIBA
01/2019 - 01/2019
2N 30IBA
09/2017 - 12/2003
2Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
05/2016 - 03/2008
2protocatechuic acidIBA
01/2016 - 06/2014
2Indicators and Reagents (Reagents)IBA
09/2012 - 07/2008
2Ethanol (Ethyl Alcohol)IBA
07/2012 - 11/2008
21,3-butadiene (divinyl)IBA
04/2012 - 01/2002
2Ethylene Oxide (Oxirane)IBA
04/2012 - 01/2002
2MutagensIBA
04/2010 - 02/2006
2Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
12/2008 - 11/2008
2Caspase 3 (Caspase-3)IBA
11/2008 - 09/2005
2pyridineIBA
07/2008 - 04/2005
2sulforaphaneIBA
09/2005 - 12/2002
2isothiocyanic acidIBA
09/2005 - 03/2003
2N-NitrosopyrrolidineIBA
01/2005 - 02/2003
24-nitrophenyl myo-inositol-1-phosphateIBA
10/2003 - 02/2003
2Hemoglobins (Hemoglobin)IBA
11/2002 - 04/2002
1nornicotineIBA
11/2023
1NitritesIBA
11/2023
1E-Cigarette VaporIBA
10/2023
13-buten-2-one (methyl vinyl ketone)IBA
09/2023
1methacrylaldehydeIBA
09/2023

Therapy/Procedure

11Chemoprevention
10/2020 - 08/2002
2Intraperitoneal Injections
01/2021 - 01/2020